Publications: 2003

1. Schaider, H.,* Oka ,* M., Bogenrieder, T., Nesbit, M., Satyamoorthy, K., Berking, C., Matsushima, K., and Herlyn, M. Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8. Int. J. Cancer 103: 335-43, 2003.* Equal contribution.      PDF version available

2. Gruss, C.J., Satyamoorthy, K., Berking, C., Lininger, J., Nesbit, M., Schaider, H., Liu, Z-J., Oka, M., Hsu, M-Y., Shirakawa, T., Li, G., Bogenrieder, T., Carmeliet, P., El-Deiry, W.S., Eck, S.L., Rao, J.S., Baker, A.H., Bennett, J.T., Crombleholme, T.M., Velazquez, O., Karmacharya, J., Margolis, D.J., Wilson, J.M., Detmar, M., Skobe, M., Robbins, P.D., Buck, C., and Herlyn, M. Stroma formation and angiogenesis by induced expression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. J. Invest. Derm. 120: 683-692, 2003.   PDF version available

3. Meier, F., Caroli, U., Satyamoorthy, K., Schittek, B., Bauer, J., Berking, C., Möller, H., Maczey, E., Rassner, G., Herlyn, M., and Garbe, C. Basic fibroblast growth factor but not Mel-CAM and/or 3 integrin promotes progression of melanocytes to melanoma. Exp. Dermatol. 12: 296-306, 2003.   PDF version available

4. Velazquez, O., and Herlyn, M. The vascular phenotype of melanoma metastasis. Clin. Exp. Met. 20: 229-235, 2003. (R).     PDF version available

5. Li, G., Meier, F., Berking, C., Satyamoorthy, K., Bogenrieder, T., and Herlyn, M. Function and regulation of melanoma-stromal fibroblast interactions: when seeds meet soil. Oncogene 22: 3162-3171, 2003.   PDF version available

6. Zhang, H., Satyamoorthy, K., Herlyn, M., and Rosdahl, I. All-trans retinoic acid differentially induces apoptosis in primary and metastatic melanoma cells. Carcinogenesis 24: 185-191, 2003.      PDf version available

7. Liu, Z-J., Shirakawa, T., Li, Y., Souma, A., Fairman, R., Velazquez, O.C., and Herlyn, M. Regulation of notch1 and dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol. Cell Biol. 23: 14-25, 2003.     PDF version available

8. Satyamoorthy, K., and Herlyn, M. p16INK4A and familial melanoma. Methods Mol. Biol. 222: 185-195, 2003.

9. Andl, C., Nakagawa, H., Mizushima, T., Oyama, K., Harada, H., Chruma, Herlyn, M., and Rustgi, A.K. Epidermal growth factor receptor mediates increased cell proliferation, migration and aggregation in esophageal keratinocytes in vitro and in vivo. J. Biol. Chem. 278: 1824-1830, 2003.     PDF version available

10. Satyamoorthy, K.,* Li, G.,* Gerrero, M.R., Brose, M.R., Volpe, P., Weber, B.L., Van Belle, P.A., Elder, D.E., and Herlyn, M. Constitutive mitogen-activated protein kinase activation in melanoma by both BRAF mutations and autocrine growth factor stimulation. Cancer Res. 63: 756-759, 2003. Equal contribution.     PDF version available

11. Marinocola, F.M., Wang, E., Herlyn, M., Seliger, B., and Ferrone S. Tumors as elusive targets for immunotherapy. Trends Immunol., 23 : 334-341, 2003 .     PDF version available

12. Kalabis, J., Patterson, M.J., Gimotty, P., Enders, G.H., Marian, B., Iozzo, R.V., Rogler, G., and Herlyn, M. Stimulation of human colonic epithelial cells by leukemia inhibitory factor is dependent on collagen-embedded fibroblasts in organotypic culture. FASEB J., Published on-line April 8, 2003 .     PDF version available

13. Li, G., Kalabis, J., Xu, X., Meier, F., Oka , M., Bogenrieder, T., Herlyn, M. Reciprocal regulation of MelCAM and AKT in melanoma. Oncogene 22: 6891-6899, 2003.    PDF version available

14. Cook, LA, Donatien, PD, Smith AG, Murphy, M,Jones, M, Herlyn, M, Bennet, DC, Leonard, JH, Sturm, RA: Human melanoblasts in culture: Expression of Brn-2/POU3F2 and synergistic regulation of FGF2, SCF and ET3. J. Invest. Dermatol., 121: 1150-1159, 2003.   PDF version available

15. Liu, Z.J., Souma, A., Snyder, R., Fairman, R.M., Herlyn, M., and Velazquez, O. ß3 intergin-mediated vascular network formation is VEGF induced and involves the RAS and PI3 kinase signalling pathways. FASEB J. 17: 1931-1933, 2003. PDF version available

16. Bogenrieder, T, Elder, D.E., Herlyn, M. Molecular and cellular biology. In: Cutaneous Melanoma, 4th edition, C. Balch, ed., Quality Medical Publ., St Louis, MO, pp. 713-751, 2003 (R).

17. Bogenrieder, T. and Herlyn, M.: Axis of evil: Molecular mechanisms of cancer metastasis. Oncogene 42: 6524-6536, 2003 (R).   PDF version available

18. Song, J.H., Song, D.K., Herlyn, M., Petruk, K.C., and Hao, C: Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1ß-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells. Clin. Cancer Res. 9: 4255-4266, 2003.    PDF version available

19. Tuveson, D. A., Weber, B.L., and Herlyn, M.: BRAF as a potential therapeutic target in melanoma and other malignancies. Cancer Cell 4:95-8, 2003 (R).   PDF version available

20. Liu, Z-J and Herlyn, M.: Slit-Robo: Neuronal guides signal tumor angiogenesis. Cancer Cell 4: 1-2, 2003 (R).    PDF version available

21. Hingorani, S.R., Jacobetz, M.A., Robertson, G., Herlyn, M., Tuveson, D.: Suppression of BRAFv599e in human melanoma abrogates transformation. Cancer Res. 63: 5198-5202, 2003.    PDF version available

22. Hirst, C.J., Herlyn, M., Cattini, P.A., Kardami, E: High levels of CUG-initiated FGF-2 expression cause chromatincompaction, decreased cardiomyocyte mitosis, and cell death. Mol Cell Biochem. 246: 111-116, 2003.     PDF version available

24. Smalley, K.S., and Herlyn, M. The great escape: Another way for melanoma to leave physiological control? J. Invest. Dermatol. 121: ix, 2003 (R). PDF version available

24. Herlyn, M., and Guerry, D IV. Meeting Report: First International Melanoma Research Congress. Cancer Biol. Therapy: 2:721-724, 2003. (R)    PDF version available