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University of the Sciences
600 South 43rd Street
Philadelphia, PA 19104-4495
215-596-8800

 

The Wistar Institute
3601 Spruce Street
Philadelphia, PA 19104
215-898-3700

Advanced Graduate Courses: CB 813 Molecular Cancer Therapeutics

This course provides the third segment of the advanced curriculum and provides program graduate students with an in-depth and mechanistic understanding of the process of drug discovery thematically linked to current therapeutic approaches for cancer treatment.

This course fills an important gap in traditional cancer biology curricula by merging basic elucidation of cancer pathways with the most up-to-date strategies in cancer therapy and cancer prevention, covering all critical aspects of drug discovery, drug development, and regulatory drug approval. The course is the most "translational" component in the overall cancer biology curriculum and involves a series of 1-hour lectures. A course outline and lecture assignment is below.

 

                            Lecture title      

1

Cancer therapy today

2

Structure-based drug design

3

Molecular drug screening/assay design

4

Computational modeling in drug design

5

Pharmacology/pharmacokinetics

6

Drug interactions

7

Nanotechnology

8

Preclinical mouse modeling of cancer

9

Cancer biomarkers

10

Molecular epidemiology

11

Molecular profiling of cancer

12

Clinical trials

13

Anti-tumor immunotherapies

14

Intellectual property

15

Marketing and commercialization

 

Student evaluation of the course and course lecturers will be conducted at the end of the Molecular Cancer Therapeutics course.