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Participating Institutions & Faculty

Participating Institutions and Faculty

UPenn Department of Chemistry

Graduate Group in Biochemistry and Molecular Biophysics


The Wistar Institute

Name Primary Appointment (s) [Graduate Group(s)]/ Role in Program Research Interest
Susan Janicki, Ph.D. The Wistar Institute/Trainer Enzyme mechanisms in gene regulation and epigenetic inheritance studied in living cells
Paul Lieberman, Ph.D. The Wistar Institute/Trainer Molecular mechanisms of viral chromosome stability and gene regulation with focus on interactions between viral activators and cellular coactivators
Ronen Marmorstein, Ph.D. The Wistar Institute/Program Director/Trainer Structural and chemical studies of proteins associated with chromatin regulation and cancer
Ellen Puré, Ph.D. The Wistar Institute/Trainer Molecular and cellular basis for inflammation in human disease
Emmanuel Skordalakes, Ph.D. The Wistar Institute/Trainer Molecular basis for telomere replication and telomerase regulation
David Speicher, Ph.D. The Wistar Institute/Trainer Macromolecular interaction mechanisms and thermodynamics in complex protein systems

 

University of Pennsylvania School of Medicine

SOM - School of Medicine
BMB - Biochemistry and Molecular Biophysics
PHRM - Pharmacy
Shelley Berger, Ph.D. UPenn SOM (BMB)/Trainer Genetics and biochemistry of enzymes that regulate transcription and chromatin
Ian Blair, Ph.D. UPenn SOM (PHRM, BMB)/Trainer Oxidative stress, carcinogenesis, and cardiovascular disease
William DeGrado, Ph.D. UPenn SOM (PHRM, BMB)/Co-Program Director, Trainer De novo design, synthesis, and characterization of proteins and peptides
Alan Diehl, Ph.D. UPenn SOM (BMB/CAMB )/Trainer Molecular mechanisms that determine normal versus neoplastic growth control including cell cycle regulation and cellular damage surveillance pathways
Kate Ferguson, Ph.D. UPenn SOM (BMB)/Trainer Stereochemical details of molecular interactions in signal transduction pathways
Yale Goldman, Ph.D. UPenn SOM (BMB)/Trainer Motor proteins studied by photochemistry and spectroscopy
Doron Greenbaum, Ph.D. UPenn SOM (PHRM, BMB)/Trainer Chemical biology of proteases in malaria
Harry Ischiropoulos, Ph.D. UPenn SOM (PHRM, BMB)/Trainer Redox-regulated post-translational protein modifications and signaling pathways
Rahul M. Kohli, M.D., Ph.D. UPenn SOM (BMB)/Trainer

Chemical probes of enzymes that purposefully mutate DNA in immune defense or pathogen evolution

 
Mark Lemmon, Ph.D. UPenn SOM (PHRM, BMB)/Trainer Molecular/structural basis for growth factor receptor signaling
Trevor Penning, Ph.D. UPenn SOM (PHRM, BMB)/Trainer Structure-function and inhibitor design of steroid hormone transforming addo-keto reductases
Greg Van Duyne, Ph.D. UPenn SOM (BMB)/Trainer Structural biochemistry of RNA processing, DNA recombination and chromosome segregation machinery
Sergei Vinogradov, Ph.D. UPenn SOM (BMB)/Trainer Probes and methods for optical microscopy and imaging
Josh Wand, Ph.D. UPenn SOM (BMB)/Trainer Protein structure, dynamics & function. NMR spectroscopy; Protein-ligand interactions; Molecular recognition and 
drug design
James Shorter, Ph.D. UPenn SOM (BMB)/Trainer Structural and chemical studies of protein disaggregases and prions

 

University of Pennsylvania School of Arts and Sciences

SOM - School of Medicine
SAS - School of Arts and Sciences
CHEM - Chemistry
David Christianson, Ph.D. UPenn SAS (CHEM)/Trainer Structural and chemical biology of metalloenzymes, terpene biosynthesis and metabolism, arginine catabolism and sexual arousal
Barry Cooperman, Ph.D. UPenn SAS (CHEM)/Trainer Biochemistry and enzymology of pyrophosphates, serpins, ribonucleotide reductase and E. coli ribosomes
Ivan Dmochowski, Ph.D. UPenn SOM (CHEM)/Trainer New molecular imaging probes; gene photoregulation; bio-nanomaterials
Feng Gai, Ph.D. UPenn SAS (CHEM)/Trainer Structure-function of protein folding and dynamics, RNA folding and dynamics, protein-protein interaction
Marisa Kozlowski, Ph.D. UPenn SOM (CHEM)/Trainer Identification of new ligands for asymmetric synthesis using database mining, functionality mapping, theoretical calculations of selectivities, and QSAR techniques
James Petersson, Ph.D. UPenn SAS (CHEM)/Trainer Chemistry of neuronal signaling proteins
Jeff Saven, Ph.D. UPenn SAS (CHEM)/Trainer Theoretical and computational methods for understanding and designing protein folds and enzymes
Amos Smith Ph.D. UPenn SAS (CHEM)/Trainer Natural product synthesis, bioorganic chemistry and materials science
Jeff Winkler Ph.D. UPenn SAS (CHEM)/Trainer Synthesis of natural and unnatural products; enzyme inhibitor design

 

University of Pennsylvania School of Arts and Sciences

SOM - School of Medicine
SAS - School of Arts and Sciences
CHEM - Chemistry
David Christianson, Ph.D. UPenn SAS (CHEM)/Trainer Structural and chemical biology of metalloenzymes, terpene biosynthesis and metabolism, arginine catabolism and sexual arousal
Barry Cooperman, Ph.D. UPenn SAS (CHEM)/Trainer Biochemistry and enzymology of pyrophosphates, serpins, ribonucleotide reductase and E. coli ribosomes
Ivan Dmochowski, Ph.D. UPenn SOM (CHEM)/Trainer New molecular imaging probes; gene photoregulation; bio-nanomaterials
Feng Gai, Ph.D. UPenn SAS (CHEM)/Trainer Structure-function of protein folding and dynamics, RNA folding and dynamics, protein-protein interaction
Marisa Kozlowski, Ph.D. UPenn SOM (CHEM)/Trainer Identification of new ligands for asymmetric synthesis using database mining, functionality mapping, theoretical calculations of selectivities, and QSAR techniques
James Petersson, Ph.D. UPenn SAS (CHEM)/Trainer Chemistry of neuronal signaling proteins
Jeff Saven, Ph.D. UPenn SAS (CHEM)/Trainer Theoretical and computational methods for understanding and designing protein folds and enzymes
Amos Smith Ph.D. UPenn SAS (CHEM)/Trainer Natural product synthesis, bioorganic chemistry and materials science
Jeff Winkler Ph.D. UPenn SAS (CHEM)/Trainer Synthesis of natural and unnatural products; enzyme inhibitor design