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The laboratory of Hildegund C.J. Ertl, M.D., focuses on pre-clinical development of vaccines to infectious diseases and cancer, emphasizing basic immunological mechanisms that influence vaccine efficacy. Specifically, the laboratory explores viral recombinant vaccines based on chimpanzee-derived adenoviral vectors. Major ongoing projects include a preventive vaccine to rabies virus, a therapeutic cancer vaccine targeting human papillomavirus which is associated with cervical cancer, vaccines to prevent human immunodeficiency virus (HIV) infection, and a universal vaccine against influenza A virus.
The team is composed of senior scientists, technicians, post- and pre-doctoral fellows, part-time undergraduate students and intern high school students.
The microscope in the image belonged to William E. Horner, M.D., a collaborator with Caspar Wistar, M.D., in the early 1800s.
Dr. Horner, a lecturer at the University of Pennsylvania, was a pioneer of the use of microscopes in anatomical and medical research. He authored Special Anatomy and Histology, a seminal text on the subject.