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The Wistar Institute
Room 283
3601 Spruce Street
Philadelphia, PA 19104

Telephone: (215) 898-3855

Dr. Ertl (215) 898-3863

Fax (215) 898-3868

email: ertl@wistar.org

Introduction

The laboratory of Hildegund C.J. Ertl, M.D., focuses on pre-clinical development of vaccines to infectious diseases and cancer, emphasizing basic immunological mechanisms that influence vaccine efficacy. Specifically, the laboratory explores viral recombinant vaccines based on chimpanzee-derived adenoviral vectors. Major ongoing projects include a preventive vaccine to rabies virus, a therapeutic cancer vaccine targeting human papillomavirus which is associated with cervical cancer, vaccines to prevent human immunodeficiency virus (HIV) infection, and a universal vaccine against influenza A virus.

The team is composed of senior scientists, technicians, post- and pre-doctoral fellows, part-time undergraduate students and intern high school students.