Table of Fluorochromes

This is a table of characteristics for fluorochromes used in flow cytometry, within groups, roughly in order of excitation wavelength.
Colors you might see with a capable browser are only a rough approximation.

Probe Ex (nm) Em (nm) MW Notes
Reactive and conjugated probes
Hydroxycoumarin 325 386 331 Succinimidyl ester
Aminocoumarin 350 445 330 Succinimidyl ester
Methoxycoumarin 360 410 317 Succinimidyl ester
Cascade Blue 375;400 423 596 Hydrazide
Lucifer yellow 425 528
NBD 466 539 294 NBD-X
R-Phycoerythrin (PE) 480;565 578 240,000
PE-Cy5 conjugates 480;565;650 670 aka Cychrome, R670, Tri-Color, Quantum Red
PE-Cy7 conjugates 480;565;743 767
Red 613 480;565 613 PE-Texas Red
Fluorescein 495 519 389 FITC; pH sensitive
BODIPY-FL 503 512
Cy3 512;552 565,615
TRITC 547 572 444 TRITC
X-Rhodamine 570 576 548 XRITC
Lissamine Rhodamine B 570 590
PerCP 490 675 Peridinin chlorphyll protein
Texas Red 589 615 625 Sulfonyl chloride
Cy5 625-650 670
Cy7 743 767 1,001
Allophycocyanin (APC) 650 660 104,000
TruRed 490,675 695 PerCP-Cy5.5 conjugate
APC-Cy7 conjugates 650;755 767 PharRed
Nucleic acid probes
Hoechst 33342 343 483  616  AT-selective
DAPI 345 455  AT-selective
Hoechst 33258 345 478  624  AT-selective
SYTOX Blue 431 480  ~400  DNA
Chromomycin A3 445 575  CG-selective
Mithramycin 445 575
YOYO-1 491 509   1270.65
SYTOX Green 504 523  ~600  DNA
SYTOX Orange 547 570  ~500  DNA
Ethidium Bromide 493 620  394.31
7-AAD 546 647  7-aminoactinomycin D, CG-selective
Acridine Orange 503 530/640 DNA/RNA
TOTO-1, TO-PRO-1 509 533 Vital stain, TOTO: Cyanine Dimer
TO-PRO: Cyanine Monomer
Thiazole Orange 510 530
Propidium Iodide (PI) 536 617 668.4
TOTO-3, TO-PRO-3 642 661
LDS 751 543;590 712;607  471.98  DNA (543ex/712em), RNA (590ex/607em)
Cell function probes
Indo-1 361/330 490/405 1010 AM ester. Low/High Ca++,
Fluo-3 506 526 855 AM ester. pH > 6
DCFH 505 535 529 2'7'Dichorodihydrofluorescein, oxidized form
DHR 505 534 346 Dihydrorhodamine 123, oxidized form,
light catalyzes oxidation
SNARF 548/579 587/635 pH 6/9
Fluorescent Proteins
Y66F 360 508
Y66H 360 442
EBFP 380 440  (Clonetech) Quantum yield 0.18
Wild Type 396,475 508,503
GFPuv 385 508  (Clonetech)
ECFP 434 477  (Clonetech) Quantum yield 0.40
Y66W 436 485
S65A 471 504
S65C 479 507
S65L 484 510
S65T 488 511
EGFP 489 508  (Clonetech) Quantum yield 0.60
EYFP 514 527  (Clonetech) Quantum yield 0.61
DsRed 558 583  (Clonetech) Quantum yield 0.29
Other probes
Monochlorobimane 380 461 226 Glutathione probe
Calcein 496 517 623 pH > 5

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jdc: 960130; 990930 jt 990319; 991112   Best viewed with Netscape
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