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Thanos Halazonetis, D.D.S., Ph.D.
Thanos Halazonetis, D.D.S., Ph.D., was a member of the Wistar faculty from 1993 to 2006, when he became a professor in the departments of molecular biology and biochemistry at the University of Geneva, Switzerland. In addition to his post at the University of Geneva, he is also currently an adjunct professor in the Molecular and Cellular Oncogenesis Program at Wistar.
Halazonetis’s research has significantly advanced scientific understanding of cell-cycle checkpoints and DNA damage-control mechanisms, contributing important insights into the workings of the p53 tumor suppressor pathway and the biogenesis of cancer generally. Studies have focused on the fact that cells undergo a carefully orchestrated cell-division process in order to replicate, with rigorous checkpoint mechanisms in place to ensure that each step in the process is properly executed before the cell moves on to the next step. Investigations in the Halazonetis laboratory explored the details of this process and, particularly, how defects might be linked to the development of cancer.
Halazonetis was awarded his Ph.D. in genetics from Harvard University in 1989 after earning a D.D.S. at the University of Athens in 1982 and taking additional graduate training at Tufts University. He had a postdoctoral fellowship at Harvard Medical School and then worked at Merck Sharp Dohme Research Laboratories before arriving at Wistar as an assistant professor in 1993. Halazonetis was promoted to associate professor at Wistar in 2000 and was then promoted to full professor in 2005.
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