Human Melanoma Cell Lines

Inventor: Meenhard Herlyn

Tech ID: HM-11RR

Description: Wistar researchers have established a collection of cell lines from melanoma patients with a wide range of disease severity. Cell lines have been established from specimens that represent each of the major steps in the progression of melanoma: (1) common acquired nevus, (2) dysplastic nevus, (3) radial growth phase primary melanoma, (4) vertical growth phase primary melanoma and (5) metastatic melanoma. In some cases, this collection includes multiple cell lines from the same individual at different stages in the disease progression. (See The Wistar Melanoma (WM) Cell Lines in HUMAN CELL CULTURE, Vol. I, 259-274, 1999)

Key Words: Research tool, drug screening, cancer, tumor antigens

Applications and Advantages: The Wistar melanoma cell lines may be useful in identification of genetic, antigenic and other changes that arise during the progression of melanoma. These cell lines may also be useful to identify novel tumor antigens.

Licensing Opportunity: These cell lines are available for non-exclusive license for research and/or product development.

Contact:

Meryle J. Melnicoff
Director, Business Development
The Wistar Institute
3601 Spruce Street
Philadelphia, PA 19104
Phone: (215) 898-0049
Fax: (215) 573-2456
melnicoff@wistar.org

Last Updated: Mar-01