Wistar Wire: Cancer

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Hope is what drives biomedical research. It is the conviction that the future is brighter and that we can do something to ease suffering from disease. For Ed Ryan, chair of Wistar’s Leadership Council, hope is the secret for The Wistar Institute’s success.
Cancer
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Giving is in fashion. Building on their ongoing commitment to breast cancer research, QVC, Inc., and the Fashion Footwear Association of New York (FFANY) recently announced a $140,000 grant to fund breast cancer research at The Wistar Institute. The grant will support study of an aggressive form of the disease, called “triple negative” breast cancer, in the lab of Dario C. Altieri, M.D., director of Wistar’s Cancer Center.
Cancer, Funding
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The phenomenon of oncogene-induced senescence allows damaged cells to, essentially, hibernate in a state where they are alive, yet not reproducing. The moles (or nevi) you see on skin are the most obvious example. The laboratory of Wistar's Rugang Zhang, Ph.D., has uncovered what drives senescence: DNA building blocks. Remove these building blocks and the cell stops dividing. Replenish the supply, and the cell turns cancerous...
Cancer
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As we file our state taxes, our Pennsylvania friends and neighbors are contributing directly to cancer research through the PA Breast Cancer Coalition’s Refunds for Research program. This week, the PBCC announced that Wistar’s Ramin Shiekhattar, Ph.D., will receive a $50,000 grant to track down the molecular pathways that allow mutations in BRCA1, BRCA2, and PALB2 genes to drive breast and ovarian cancer.
Cancer, Funding