Advanced Graduate Courses: CB 811 Cancer

This course provides prospective graduate students with a rigorous and comprehensive understanding of the mechanisms that underlie the genesis and progression of human cancer. The lectures build on the basic science knowledge acquired in the graduate core curriculum at USciences, which is a mandatory requirement before students can access this integrated cancer biology course.

This basic cancer course expands the biological concepts of pathophysiological pathways of biochemistry, molecular and cellular biology, and genetics that contribute to cancer pathogenesis. The course is offered as individual lectures of 1–3 hours each and involves faculty members from both Wistar and USciences. Further discussion will identify the best setting for the course, either at USciences or Wistar. An outline and lecture assignment is presented below.

 

Lecture title

1

Nature of cancer

2

Cell division and the cell cycle

3

Oncogenes

4

Tumor suppressors

5

Growth factor signaling

6

DNA damage and repair

7

Genomic instability

8

Apoptosis

9

Angiogenesis

10

Tumor microenvironment

11

Immortalization and senescence

12

Tumor immunology

13

Metastasis

14

Cancer genomics