Participating Institutions and Faculty
Graduate Group in Biochemistry and Molecular Biophysics
| Name | Primary Appointment (s) [Graduate Group(s)]/ Role in Program | Research Interest |
|---|---|---|
| Nadia Dahmane, Ph.D. | The Wistar Institute/Trainer | Targeted therapies for brain cancer |
| Susan Janicki, Ph.D. | The Wistar Institute/Trainer | Enzyme mechanisms in gene regulation and epigenetic inheritance studied in living cells |
| Joseph Kissil, Ph.D. | The Wistar Institute/Trainer | Molecular basis of signal transduction pathways and their function in normal and cancer conditions |
| Paul Lieberman, Ph.D. | The Wistar Institute/Trainer | Molecular mechanisms of viral chromosome stability and gene regulation with focus on interactions between viral activators and cellular coactivators |
| Ronen Marmorstein, Ph.D. | The Wistar Institute/Program Director/Trainer | Structural and chemical studies of proteins associated with chromatin regulation and cancer |
| Ellen Puré, Ph.D. | The Wistar Institute/Trainer | Molecular and cellular basis for inflammation in human disease |
| Emmanuel Skordalakes, Ph.D. | The Wistar Institute/Trainer | Molecular basis for telomere replication and telomerase regulation |
| David Speicher, Ph.D. | The Wistar Institute/Trainer | Macromolecular interaction mechanisms and thermodynamics in complex protein systems |
University of Pennsylvania School of Medicine
SOM - School of Medicine BMB - Biochemistry and Molecular Biophysics PHRM - Pharmacy |
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| Shelley Berger, Ph.D. | UPenn SOM (BMB)/Trainer | Genetics and biochemistry of enzymes that regulate transcription and chromatin |
| Ian Blair, Ph.D. | UPenn SOM (PHRM, BMB)/Trainer | Oxidative stress, carcinogenesis, and cardiovascular disease |
| William DeGrado, Ph.D. | UPenn SOM (PHRM, BMB)/Co-Program Director, Trainer | De novo design, synthesis, and characterization of proteins and peptides |
| Kate Ferguson, Ph.D. | UPenn SOM (BMB)/Trainer | Stereochemical details of molecular interactions in signal transduction pathways |
| Yale Goldman, Ph.D. | UPenn SOM (BMB)/Trainer | Motor proteins studied by photochemistry and spectroscopy |
| Doron Greenbaum, Ph.D. | UPenn SOM (PHRM, BMB)/Trainer | Chemical biology of proteases in malaria |
| Mark Lemmon, Ph.D. | UPenn SOM (PHRM, BMB)/Trainer | Molecular/structural basis for growth factor receptor signaling |
| Trevor Penning, Ph.D. | UPenn SOM (PHRM, BMB)/Trainer | Structure-function and inhibitor design of steroid hormone transforming addo-keto reductases |
| Greg Van Duyne, Ph.D. | UPenn SOM (BMB)/Trainer | Structural biochemistry of RNA processing, DNA recombination and chromosome segregation machinery |
| Josh Wand, Ph.D. | UPenn SOM (BMB)/Trainer | Protein structure, dynamics & function. NMR spectroscopy; Protein-ligand interactions; Molecular recognition and drug design |
| James Shorter, Ph.D. |
UPenn SOM (BMB)/Trainer | Structural and chemical studies of protein disaggregases and prions |
University of Pennsylvania School of Arts and Sciences
| SOM - School of Medicine SAS - School of Arts and Sciences CHEM - Chemistry |
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| Jeff Bode, Ph.D. | UPenn SAS (CHEM)/Trainer | Peptides, Bioorganic Chemistry, Catalysis, Bioimaging |
| David Christianson, Ph.D. | UPenn SAS (CHEM)/Trainer | Structural and chemical biology of metalloenzymes, terpene biosynthesis and metabolism, arginine catabolism and sexual arousal |
| Barry Cooperman, Ph.D. | UPenn SAS (CHEM)/Trainer | Biochemistry and enzymology of pyrophosphates, serpins, ribonucleotide reductase and E. coli ribosomes |
| Ivan Dmochowski, Ph.D. | UPenn SOM (CHEM)/Trainer | New molecular imaging probes; gene photoregulation; bio-nanomaterials |
| Feng Gai, Ph.D. | UPenn SAS (CHEM)/Trainer | Structure-function of protein folding and dynamics, RNA folding and dynamics, protein-protein interaction |
| Marisa Kozlowski, Ph.D. | UPenn SOM (CHEM)/Trainer | Identification of new ligands for asymmetric synthesis using database mining, functionality mapping, theoretical calculations of selectivities, and QSAR techniques |
| James Petersson, Ph.D. | UPenn SAS (CHEM)/Trainer | Chemistry of neuronal signaling proteins |
| Jeff Saven, Ph.D. | UPenn SAS (CHEM)/Trainer | Theoretical and computational methods for understanding and designing protein folds and enzymes |
| Amos Smith Ph.D. | UPenn SAS (CHEM)/Trainer | Natural product synthesis, bioorganic chemistry and materials science |
| Jeff Winkler Ph.D. | UPenn SAS (CHEM)/Trainer | Synthesis of natural and unnatural products; enzyme inhibitor design |