Hildegund C.J. Ertl, MD

Ertl

Blaszczyk-Thurin

Hildegund C.J. Ertl (1996-2002)

  1. Xiang, Z.Q., Yang, Y., Wilson, J.M. and Ertl, H.C.J. 1996. A replication-defective recombinant adenovirus serves as a highly efficient vaccine carrier for the rabies virus glycoprotein. Virology, 219: 220-227.

  2. Ertl, H.C.J. and Xiang, Z.Q. 1996. DNA vaccines to rabies virus: effects of cytokines on the immune response. Vaccines 1996: 83-86.

  3. Xiang, Z.Q., Yang, Y., Wilson, J.H. and Ertl, H.C.J. 1996. Rabies vaccines based on E1 deleted recombinant adenovirus. Vaccines 1996: 189-193.

  4. Ertl, H.C.J., Varga, I., Xiang, Z.Q., Kaiser, K., Stephens, L. and Otvos, L., Jr. 1996. Poly (DL-lactide-co-glycolide) microspheres as carriers for peptide vaccines. Vaccine 14: 879-8

  5. Ertl, H.C.J. and Xiang, Z.Q. 1996. Genetic immunization. Viral Immunology 9:189-193.

  6. Ertl, H.C.J. and Xiang, Z.Q. 1996. Novel vaccine approaches. J. Immunol. 156: 3579-3582.

  7. Otvös, L., Jr., Cappelletto, B., Varga, I., Wade, J.D., Xiang, Z.Q., Kaiser, K., Stephens, L.J. and Ertl, H.C.J. 1996. The effects of post-translational side-chain modifications on the stimulatory activity, serum stability and conformation of synthetic peptides carrying T helper cell epitopes. Biochimica et Biophysica Acta 1313: 11-19.

  8. Wang, Y., Xiang, Z., Pasquini, S. and Ertl, H.C.J. 1997. Immune response to neonatal genetic immunization. Virology 228: 278-284.

  9. Ertl, H.C.J. 1997. The perpetual network theory and its putative application: 21 years later. In: Idiotypes in Medicine: Autoimmunity, Infection and Cancer. Elsevier Science B.V. Y. Shoenfeld, R.C. Kennedy and S. Ferrone, editors.

  10. Wang, Y., Xiang, Z., Pasquini, S. and Ertl, H.C.J. 1997. The use of an E1-deleted, replication-defective adenovirus recombinant expressing the rabies virus glycoprotein for early vaccination of mice against rabies virus. J. Virol. 71: 3677-3683.

  11. Xiang, Z.Q., He, Z., Wang, Y. and Ertl, H.C.J. 1997. The effect of interferon-g on genetic immunization. Vaccine 15: 896-898.

  12. Xiang, Z.Q., Pasquini, S., He, Z., Deng, H., Wang, Y., Blaszczyk-Thurin, M. and Ertl, H.C.J. 1997. Genetic Vaccines- A revolution in vaccinology? In Plasmid DNA Vaccination: Principles and Applications, Springer Seminars in Immunopathology 19: 257-268.

  13. Pasquini, S., Xiang, Z., Wang, Y., He, Z., Deng, Z., Blaszczyk-Thurin, M. and Ertl, H.C.J. 1997. Cytokines and costimulatory molecules as genetic adjuvants. Immunol. Cell Biol. 75: 397-401.

  14. Wang, Y., Xiang, Z., Pasquini, S. and Ertl, H.C.J. 1998. The effect of passive immunization or maternally transferred immunity on the antibody response to a genetic vaccine to rabies virus. J. Virol. 72: 1790-1796.

  15. Jooss, K., Ertl, H.C.J. and Wilson, J.M. 1998. CTL target proteins and their MHC class I restriction in response to adenoviral vectors delivered to mouse liver. J. Virol. 72: 2945-2954.

  16. Wloch, M.K., Pasquini, S., Ertl, H.C.J. and Pisetsky, D.S. 1998. The influence of DNA sequence on the immunostimulatory properties of plasmid DNA vectors. Hum. Gene Ther. 9: 1439-1447.

  17. Otvos, L. Jr., Hoffmann, R., Xiang, Z.Q., O, I., Deng, H., Wysocka, M., Pease, A.M., Blaszczyk-Thurin, M. and Ertl, H.C.J. 1998. A monoclonal antibody to a multiphosphorylated, conformational epitope at the carboxy-terminus of p53. Biochim. Biophys. Acta. 1404: 457-474.

  18. Ertl, H.C.J., Deng, H., Pasquini, S., Wang, Y. and Xiang, Z. 1998. Augmentation of the immune response by DNA vaccines that contain cytokine genes. Proceedings of the 1998 National Immunology Meeting (Mark Ballow, M.D., Editor), Bodega Bay, CA.

  19. Hoffmann, R., Ertl, H.C.J., Rovera, G. and Otvos, L., Jr. 1998. Low scale multiple synthesis and DNA hybridization of peptide nucleic acids (PNA). Peptides: Chemistry, Structure and Biology (J.P. Tam and P.T.P. Kaumaya, eds.) Escom Science Publisher, Leiden.

  20. Hoffmann, R., Chang, E., Ertl, H.C.J. and Otvos, L., Jr. 1998. Phoshopeptide models of the C-terminal basic domain of p53. In: Peptides: Chemistry, Structure and Biology (J.P. Tam and P.T.P. Kaumaya, eds.) Escom Science Publisher, Leiden.

  21. Ertl H.C.J., Pasquini, S., He, Z., Deng, H., Showe, L., Giles-Davis, W., Wang, Y., O, I., Martson, H., Blaszscyk-Thurin, M. and Xiang, Z. 1998. Genetic Adjuvants. In: Methods in Molecular Medicine, Vol. 9, DNA Vaccines; Methods and Protocols (D.B. Lowrie and R. Whalen eds) Humana Press Inc., Totowa, NJ. pp 251-260.

  22. Ertl, H.C.J., Xiang, Z.Q., Pasquini, S. and D. Kowalczyk. 1998. Vaccines: Presentation. Encyclopedia of Life Science (S. Robertson and R. Fairbairn, eds.) Macmillan Reference Ltd., London, UK. In Press.

  23. Hoffman, R. Ertl, H.C.J., Pease, A.M., Rovera, G., Otvos, Jr. L. 1998. Optimization of Synthesis and DNA Hybridization of Peptide Nucleic Acids. In: Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. Peptides, Proteins and Nucleic Acids: Small Molecule Organic Chemical Diversity (Roger Epton, ed.).Mayflower Scientific Limited, Birmingham. Pp.311- 314.

  24. Kowalczyk, D. and Ertl, H.C.J. 1999. Immune responses to DNA vaccines. In: Cellular and Molecular Life Sciences (P. Jolläs Ed.) BirkhÑuser Publishing Ltd., Basel, CH. 55: 751-770.

  25. Reddy, S.T. and Ertl, H.C.J. 1999. The potential use of DNA vaccines for neonatal immunization. Current Opinion in Molecular Therapeutics Vol. 1 (E. Hutchinson Ed.) Current Drugs Ltd., Middlesex, UK, pg. 22-29.

  26. Xiang, Z.H. and Ertl, H.C.J. 1999. Induction of mucosal immunity with a replication-defective adenoviral recombinant. Vaccine 17 : 2003-2008.

  27. Xiang, Z.Q., Pasquini, S. and Ertl, H.C.J. 1999. Induction of genital immunity by DNA priming and intranasal booster immunization with a replication-defective adenoviral recombinant. J. Immunol. 162: 6716-6723.

  28. Pasquini, S., Deng, H., Reddy, S.T., Giles-Davis W. and Ertl, H.C.J. 1999. The effect of CpG sequences on the B cell response to a viral glycoprotein encoded by a plasmid vector. Gene Therapy. 6:1448-1455.

  29. Irwin, D.J., Jackson, A.C., Wunner, W.H. and Ertl, H.C.J. Basis of rabies virus neurovirulence in mice: Expression of major histocompatibility complex class I and class II mRNA in mouse brains. J. NeuroVirology 5: 485-494.

  30. Ertl, H.C.J. 1999. Clinical Simulations: In the Management of Rabies Exposure. Sponsored by Albert Einstein College of Medicine & Montefiore Medical Center. 1: 1-16.

  31. He, Z., Wlazlo, A.P.,Kowalczyk, D., Cheng, J., Xiang, Z.Q., Giles-Davis, W. and Ertl, H.C.J. 2000. Viral Recombinant Vaccines to the E6 and E7 Antigens of HPV-16. Virology, 270: (1) 146-161.

  32. Oyaski, M. and Ertl, H.C.J. 2000. DNA Vaccines. Science & Medicine. 7: 30-43.

  33. Otvos, L. Jr., Pease, A.M., Bokonyi, K., Giles-Davis, W., Rogers, M.E., Hintz, P.A., Hoffmann, R. and Ertl, H.C.J. 2000. In situ identification of T helper cell hybridoma with a cellulose-bound peptide antigen. J. Immuno. Meth. 233: 95-105.

  34. Fields, P.A., Kowalczyk, D.W., Arruda, V.R., McCleland, M.L., Armstrong, E., Hagstrom, J.N., Pasi, K.J., Ertl, H.C.J., Herzog, R.W., High, K.A. 2000. Role of vector in activation of T cell subsets in immune responses against the secreted transgene product factor IX. In press.

  35. Tims, T. Briggs, D. J., Davis, R., Moore, S.M., Xiang, Z.Q. Ertl, H.C.J., Fu, Z.F. Dogs vaccinated with recombinant adenovirus glycoprotein develop high titers of neutralizing antibodies. Vaccines, In press.

  36. Kowalczyk, D., Wlazlo, A., Giles-Davis, W., Ertl, H.C.J. 2000. Staining of antigen activated lymphocytes (SAAL): A highly specific method for amplification of tumor-specific CD8+ T cells. J. Immunol. Meth. In press.

  37. Otvos, Jr., L., Bokonyi, K., Varga, I., Otvos, B.I., Hoffmann, R., Ertl, H.C.J., Wade, J.D., McManus, A.M., Craik, D.J., Bulet, P. 2000. Insect peptides with improved protease-resistance protect mice against bacterial infection. Protein Science: 9: 742 ­ 749.

Magda Blaszczyk-Thurin (1996-2000)

  1. Blaszczyk-Thurin, M., Murali, R., Westerink, J., Steplewski, Z., and Kieber-Emmons, T. 1996. Molecular recognition of Lewis antigens by monoclonal antibodies. Prot. Eng. Protein Engineering 9: 447-459.

  2. Pasquini, S., Xiang, Z., Wang, Y., He, Z., Deng, H., Blaszczyk-Thurin, M., and Ertl, H.C.J. 1997. Cytokines and co-stimulatory molecules as genetic adjuvants.1997. Immunol. and Cell Biol. 75, 397-401.

  3. Xiang Z.Q., Pasquini S., He Z., Deng H., Wang Y., Blaszczyk-Thurin M., and Ertl H.C.J. 1997. Genetic vaccines-a revolution in vaccinology? Springer Seminars in Immunopathology. 19: 257-268.

  4. Otvos, L. Jr., Hoffmann, R., Xiang, Z.Q., O, I., Deng, H., Wysocka, M., Pease, A.M., Blaszczyk-Thurin, M., and Ertl, H.C.J. 1998. A monoclonal antibody to a multiphosphorylated, conformational epitope at the carboxy-terminus of p53. Biochim. Biophys. Acta. 1404 (3): 457-474.

  5. Xiang, Z.Q., Pasquini, S., He, Z., Deng, H., Wang, Y., Blaszczyk-Thurin, M., and Ertl, H.C.J. 1997 Genetic vaccines-a revolution in vaccinology? Springer Seminars in Immunopathology. 19, 257-268.

  6. Ertl H.C.J., Pasquini, S., He, Z., Deng, H., Showe, L., Giles-Davis, W., Wang, Y., O, I., Martson, H., Blaszscyk-Thurin, M., and Xiang, Z. 1999. Genetic Adjuvants. In: Methods in Molecular Medicine, Vol. 9, DNA Vaccines; Methods and Protocols (D.B. Lowrie and R. Whalen eds) Humana Press Inc., Totowa, NJ. pp 251-260.

  7. Kieber-Emmons T., Luo P., Qiu J., Chang T.Y., O I., Blaszczyk-Thurin M. and Steplewski Z. 1999. Vaccination with carbohydrate peptide mimotopespromote anti-tumor responses. Nature Biotech. 17: 660-665.

  8. O I., Kieber-Emmons T., Otvos L. and Blaszczyk-Thurin M. 1999. Peptides mimicking sialyl Lewis A isolated from a