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The Wistar Institute

3601 Spruce Street

Philadelphia, PA 19104


Office: 215-898-3871


Researchers in the laboratory of Andrew J. Caton, Ph.D., aim to illuminate the mechanisms that govern the immune system’s ability to react against viruses and other pathogens, and to prevent responses against “self”--the human body’s own tissues. The laboratory strives to define the mechanisms by which T cells and B cells are regulated, and to understand how these processes fail and/or can be manipulated in infections, and in diseases such as rheumatoid arthritis, lupus, and cancer.