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University of the Sciences
600 South 43rd Street
Philadelphia, PA 19104-4495
215-596-8800

 

The Wistar Institute
3601 Spruce Street
Philadelphia, PA 19104
215-898-3700

Advanced Graduate Courses: CB 812 Molecular Mechanisms of Cancer

The Molecular Mechanisms of Cancer course builds on the knowledge acquired with the core curriculum as well as the basic Cancer course to provide pivotal examples of how a better elucidation of mechanistic cancer pathways has led to a more comprehensive understanding of individual types of cancers or, alternatively, specific aspects of critical importance in tumorigenesis, for instance, metastasis. 

This course provides program graduate students with a mechanism-driven and broad knowledge base to better incorporate the more translational set of topics covered in the third course, Molecular Cancer Therapeutics. The Molecular Mechanisms of Cancer course is taught by faculty from The Wistar Institute and will be composed of a series of 1-hour lectures. An outline for the Molecular Mechanisms of Cancer course is presented below.

 

Lecture title

1

Cancer as a genetic disease

2

EBV tumorigenesis

3

Viral tumorigenesis

4

BCR-ABL in chronic myelogenous leukemia

5

Bcl-2 in follicular lymphoma

6

BRAF signaling in melanoma

7

PTEN signaling in prostate cancer

8

Wnt pathway in colorectal cancer

9

Transcriptional control in epithelial metastasis

10

Tumor microenvironment in melanoma

11

Immunosuppression in cancer

12

Genetic regulatory networks in cancer