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The Wistar Institute

3601 Spruce Street

Philadelphia, PA 19104

 

Office: 215-898-3710

Introduction

Research in the laboratory of Ellen Heber-Katz, Ph.D., has covered a broad array of topics, centering on the genetics and molecular and cellular biology of autoimmunity, the study of the immune response to HSV and the development of T cell vaccines, and most recently wound healing and regeneration. The current studies in the Heber-Katz laboratory involve basic mammalian regeneration research applied to multiple tissue types including appendage regeneration, heart disease, and spinal cord tissue damage and basic mechanisms of DNA damage control, cell growth and differentiation, and the mapping of genes involved in these processes.

The examination of multiple organ systems has allowed these researchers to make observations in one system that can clarify issues in another system. Thus, these studies synergize each other. Finally, in studies in each of these systems, they have noted a regenerative capacity in normal mice not previously seen.