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The Wistar Institute

3601 Spruce Street

Room 214-10

Philadelphia, PA 19104

 

Office: 215-898-3791

Introduction

The research team led by Louise C. Showe, Ph.D., is using DNA microarray technology to better understand a number of diseases and conditions in which changes in the activity of multiple genes are involved. Among these are a type of cancer known as cutaneous T-cell lymphoma, septic shock, multiple sclerosis, and even obesity. Microarrays allow the scientists to survey and compare the simultaneous activity of thousands of genes in normal and diseased tissues. The ultimate aim is to improve diagnostic techniques and identify promising new targets for therapy.