Publications 2012
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Publications: 2012
1 - Li L, Fukunaga-Kalabis M, Herlyn M. Isolation and cultivation of dermal stem cells that differentiate into functional epidermal melanocytes. Methods Mol Biol. 2012;806:15-29. PDF
2 - Kalabis J, Wong GS, Vega ME, Natsuizaka M, Robertson ES, Herlyn M, Nakagawa H, Rustgi AK. Isolation and characterization of mouse and human esophogeal epithelial cells in 3D organotypic culture. Nature Protocols. 7:235-246, 2012. PDF
3 - Herlyn, M.: New Dream Team for melanoma therapy. Pig. Cell Mel. Res. 25(2): 279-280, 2012. PDF
4 - Lee, J.T., Herlyn, M.: MEK’ing the most of p53 reactivation therapy in melanoma. J Invest. Dermatol. 132: 263-265, 2012. PDF
5 - Slipcevic, A., Herlyn, M.: Narrowing the knowledge gaps in melanoma. Upsala J Med. Sci. 117:237-243, 2012. PDF
6 - Pinc A, Somasundaram R, Wagner C, Hörmann M, Karanikas G, Jalili A, Bauer W, Brunner P, Grabmeier-Pfistershammer K, Gschaider M, Lai CY, Hsu MY, Herlyn M, Stingl G, Wagner SN. Targeting CD20 in melanoma patients at high risk of disease recurrence. Mol Ther. 20(5): 1056-1062, 2012. PDF
7 - Wenzel V, Roedl D, Gabriel D, Gordon LB, Herlyn M, Schneider R, Ring J, Djabali K. Naive adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo. Biology Open. 000: 1-11, 2012. PDF
8 - Wang T, Ge Y, Xiao M, Lopez-Coral A, Azuma R, Somasundaram R, Zhang G, Wei Z, Xu X, Rauscher FJ, Herlyn M, Kaufman RE. Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature. Pigm Cell Mel Res. 25(4), 493-505, 2012. PDF
9 - Qin, J., Xie, P., Ventocilla, C., Zhou, G., Vultur, A., Chen, Q., Liu, Q., Herlyn, M., Winkler, J.D, Marmorstein, R.: Identification of a novel family of BRAFV600E inhibitors. J Med. Chem. 55: 5220-5230, 2012. PDF
10 - Furney, S.J., Turajlic, S., Fenwick, K., Lambros, M.B., Mackay, A., Ricken, G., Mitsopoulos, C., Kozarewa, I., Hakas, J., Zvelebil, M., Lord, C.J., Ashworth, A., Reis-Filho, J.S. Herlyn, M., Murata, H., Marais, R.: Genomic characterisation of acral melanoma cell lines. Pigment Cell Mel Res. 25(4): 488-492, 2012. PDF
11 - Somasundaram, R. and Herlyn, M. Melanoma Exosomes: Messengers of metastasis. Nature Medicine. 18(6): 853-854, 2012. PDF
12 - Herlyn, M. Randy Lomax: The passtionate melanoma advocate and champion of the Melanoma Research Foundation. Pigment Cell Mel Res. June 15. Epub ahead of print. PDF
13 - John, JK, Paraiso, KHT, Vito, RW, Cantini, LP, Abel, EV, Pagano, N, Meggers, E., Mathew, R., Krepler, C., Izumi, V., Fang, B., Koomen, J.M., Messina, J.L., Herlyn, M., and Smalley, K. GSK3B Inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. Journal for Investagative Dermatology. July 19. Epub ahead of print. PDF
14 - Naganuma, S, Whelan, K.A., Natsuizaka, S., Kinugasa, H., Chang, S., Subramanian, H., Rhoades, B., Ohashi, S., Itoh, H., Herlyn, M. Diehl, A.J., Gimotty, P.A. Klein-Szanto, A.H., Nakagawa, H. Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma. Am J Cancer Res. 2: 459-475, 2012. PDF
15 - Zhang, G and Herlyn, M. Human nevi - no longer precursors to melanoma? 132(9): 2133-4, 2012. PDF
16 - Kong, X., Qin, J., Li, Z., Vultur, A., Tong, L., Feng, E., Rajan, G., Liu, S., Lu, J., Liang, Z., Zheng, M., Zhu, W., Jiang, H., Herlyn, M., Liu, H., Marmorstein, R., Luo, C. Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization. Org Biomol Chem. Aug. 9, 2012. Epub ahead of print. PDF
17 - Tchou, J., Kossenkov, A.V., Chang, L., Satiga, C., Herlyn, M., Showe, L.C., Pure, E. Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles. BMC Med. Genom. Sept 6, 35:9, 2012. PDF
18 - Chae, Y.C., Caino, M.C., Lisanti, S., Gosh, J.C., Dohi, T., Danial, N.N., Villanueva, J., Ferrero, S., Vaira, V., Santambrogio, L., Bosari, S., Languino, L., Herlyn, M., Altieri, D.C. Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90. Cancer Cell 22: 331-344, 2012. PDF
19 - Wagner, S., Somasundaram, R., Herlyn, M. Immunotargeting of tumor subpopulations in melanoma patients: a paradigm shift in therapy approaches. Oncoimmunology, in press.
20 - Somasundaram, R., Villanueva, J., Herlyn, M. Intratumoral heterogeneity as a therapy resistance mechanism: Role of melanoma subpopulations. Advances in Pharmacology. 65: 335-359, 2012. PDF
21 - Facompre, N., Nakagawa, H., Herlyn, M., Basu, D. Stem-like therapy and therapy resistance in squamous cell carcinoma. Advances in Pharmacology. 65:359-365, 2012. PDF
22 - Rasanen, K. and Herlyn, M. Paracrin signaling between carcinoma cells and mesenchymal stem cells generates cancer stem cell niche via epithelial-mesenchymal transition. Cancer Discovery 2: 775-779, 2012. PDF
23 - Fukunaga-Kalabis, M. and Herlyn, M. Beyond ABC: Another mechanism of drug resistance in melanoma side population. J. Investig. Dermatol. 132: 2317-2319, 2012. PDF
24 - Wang, T. Somasundaram, R., Herlyn, M. Combination therapy of immunosytokines with Ipilumumab: A cure for melanoma? J. Invest. Dermatol, in press.
25 - Fukunaga-Kalabis, M. and Herlyn, M. Cancer: Complexion matters. Nature. Nov 15. 491: 342-343, 2012. PDF
26 - Maurer, M., Somasundaram, R., Herlyn, M., Wagner, S.N. Immunotargeting of tumor subpopulations in melanoma patients. OncoImmunology. 1(8): 1454-1456, 2012. PDF
27 - Schasyowitz, A., Bertenshaw, G., Jeffries, E., Schatz, T., Cotton, J., Villanueva, J., Herlyn, M., Krepler, C., Vultur, A., Xu, W., Yu, G.H., Schuchter, L., Clark, D.P. Functional profiling of live melanoma samples using a novel automated platform. PLOS One. 7(12): e52760, 2012. PDF
28 - Balaburski, G., Leu, J. I., Beeharry, N., Hayik, S., Andrake, S., Zhang, G., Herlyn, M. Villanueva, J., Dunbrack, R., Yen, T., George, D., Murphy, M. A modified HSP70 inhibitor shows broad activity as an anticancer agent. Mol Cancer Res, Jan 9 2012, epub. PDF
29 - Somasundaram, S., Herlyn, M. Relapse of melanoma after successful adoptive T cell therapy: escape through inflammation-induced phenotypic melanoma cell plasticity. PCMR, 2012. PDF
