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Publications 2010

Publications: 2010

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1 - Vultur, A., Villanueva, J., Herlyn, M: BRAF inhibitor unveils its potential against advanced melanoma. Cancer Cell 18: 301-302, 2010. PMID20951940  PDF

2 - Zabierowski, S.E., Herlyn, M.: Embryonic stem cells as a model to study melanocyte development. Methods Mol Biol. 584:301-316, 2010. PMID19907984  PDF

3 - Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK and Nakagawa H. Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors. Cancer Res 70: 4174-4184, 2010. PMID20424117  PDF

4 - Han MJ, Wang H, Beer LA, Tang HY, Herlyn M, Speicher DW. A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling. Proteomics. 2010 Dec;10(24):4450-62. PMID21136598  PDF

5 - Herlyn M, Nathanson KL. Taking the guesswork out of uveal melanoma. N Engl J Med. 2010 Dec 2;363(23):2256-7. PMID21083377  PDF

6 - Herlyn M. Boris Bastian. Pigment Cell Melanoma Res. 2010 Dec;23(6):834. PMID20973934  PDF

7 - Lee JT, Li L, Brafford PA, van den Eijnden M, Halloran MB, Sproesser K, Haass NK, Smalley KS, Tsai J, Bollag G, Herlyn M. PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Pigment Cell Melanoma Res. 2010 Dec;23(6):820-7. PMID20973932  PDF

8 - Villanueva, J., Vultur A, Somasundaram R, Fukunaga-kalabis M, Cipolla A, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, D’Andrea K, Pushparajan A, Hayden JE, Dahlman Brown K, Laquerre S, McArthur GA, Sosman JA, Nathanson KL and Herlyn M. Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. Cancer Cell. 2010 Dec: 18, 683-695. PMID: PMID21156298  PDF

9 - Ohashi, S., Natsuizaka, M., Yashiro-Ohtani, Y., Kalman, R. A., Nakagawa, M., Wu, L., Klein-Szanto, A.J., Herlyn, M., Diehl, J.A., Kathz, J.P., Pear, W.S., Seykora, J.T., Nakagawa, H.: NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network. Gastroenterology. 139(6): 2113-23, 2010.  PMID20801121  PDF

10 - Fukunaga-Kalabis, M., Martinez, G., Nguyen, T-T.K, Kim, D., Santiago-Walker, A., Roesch, A., Herlyn, M.: Tenascin promotes melanoma progression by maintaining the ABCB5-positive side population. Oncogene 29(46): 6115-24, 2010.  PMID20729912   PDF

11 - Aggarwal, P., Vaites, L.P., Kim, J. K., Mellert, H., Nakagawa, H., Herlyn, M., Rustgi, A., McMahon, S.B., Diehl, J.A.: Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase. Cancer Cell. 2010 Oct 19;18(4):329-40. PubMed PMID20951943;  PMC2957477  PDF

12 - Santiago-Walker, A., Herlyn, M.: The ups and downs or transcription factors in melanoma. J Natl Cancer Inst 102: 1103-1104, 2010.  PMID20660367  PDF

13 - Basu, D., Nguyen, T-T., Montone, K.T., Zhang, G., Wang, L-P., Diehl, J.A., Rustgi, A. K. Lee, J.T., Weinstein, G.S., Herlyn, M.: Mesenchymal sub-populations within squamous cell carcinomas exhibiting chemoresistance and phenotypic plasticity. Oncogene 29: 4170-4182, 2010. PMID20498638  PDF

14 - Roesch, A., Fukunaga-Kalabis, M., Schmidt, E.C., Zabierowski, S.E., Brafford, P.A., Vultur, A., Basu, D., Gimotty, P., Vogt, T., Herlyn, M.: A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. CELL 141: 583-594, 2010. PMID204782552  PDF

15 - Natsuizaka, M., Ohashi, S., Wong, G., Ahmadi, A., Kalman, R., Budo, D., Klein-Szanto, A., Herlyn, M., Diehl, A., Nakagawa, H.: Insulin-like growth factor binding protein-3 promotes transforming growth factor-ß1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells. Carcinogenesis 31: 1344-1353, 2010. PMID20513670  PDF

16 - Michaylira, C.Z., Wong, G.S., Miller, C.G., Gutierrez, C.M. Nakagawa, H., Hammond, R., Klein-Szanto, A.J., Lee, J.S., Kim, S.B., Herlyn, M., Diehl, J.A., Gimotty, P., Rustgi, A.K.: Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer. Cancer Res. 70: 5281-5291, 2010. PMID20516120  PDF

17 - Grugan, K.D., Miller, C.G., Yao, Y., Michaylira, C.Z., Ohashi, S., Klein-Szanto, A.J., Diehl, J.A., Herlyn, M., Han, M., Nakagawa, H., Rustgi, A.K.: Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal cell carcinoma invasion. Proc. Natl. Acad. Sci (USA) 107: 11026-11031, 2010. PMID20534479 PMC2890722 PDF

18 - Gaddipati, H., Herlyn, M.: Melanoma: Mutations in multiple pathways at the tumor-stroma interface. In: Cancer Genome and Tumor Microenvironment, ed. By A. Thomas-Tikhoenenko, Springer, New York, pp.455-470, 2010.

19 - Fisher, D.E., Barnhill, R., Hodi, F.S., Herlyn, M., Merlino, G., Medrano, E., Bastian, B., Landi, T.M., Sosman, J:  Melanoma from bench to bedside: meeting report from the 6th international melanoma research congress. Pigm. Cell Melanoma Res. 23: 14-26. PMID20025711  PDF

20 - Herlyn, M., Fukunaga-Kalabis, M.: What is a good model for melanoma? J Invest. Dermatol. 130: 911-912, 2010. PMID20231823  PDF

21 - Li L, Fukunaga-Kalabis M, Yu H, Xu X, Kong J, Lee JT, Herlyn M. Human dermal stem cells differentiate into functional epidermal melanocytes. J Cell Sci 123: 853-860, 2010.  PMID20159965; PMC2831759 PDF

22 - Degenhardt Y, Huang J, Greshock J, Horiates G, Nathanson K, Yang X, Herlyn M, Weber B. Distinct MHC gene expression patterns during progression of melanoma. Genes Chromosomes Cancer. 2010 Feb;49(2):144-54.   PMID19862823; PMC2796267 PDF