Molecular and Cellular Oncogenesis

The overall goal of the Molecular and Cellular Oncogenesis program is to understand normal and malignant cell growth and differentiation. 

The program’s members seek to better understand the biological impact of specific molecular events associated with tumor formation and the progression of metastatic disease. Several member laboratories study large protein complexes and cellular machines, how cellular networks respond to different signaling pathways, and how changes in global patterns of gene expression at the genetic and protein levels influence normal and disease processes. 

Program members use a variety of current and emerging investigative strategies and disciplines to create a comprehensive analysis of human diseases, including nucleotide microarrays, proteomics, computational biology, and functional genomics. The program has an emerging experimental therapeutics focus that builds on the unique biological models for regeneration and cancer.


Dario C. Altieri, M.D.
Meenhard Herlyn, D.V.M., D.Sc.
Susan Janicki, Ph.D.
Russel Kaufman, M.D.
Qin Liu, M.D., Ph.D.
Maureen Murphy, Ph.D.*
Harold C. Riethman, Ph.D.
Louise C. Showe, Ph.D.***
David W. Speicher, Ph.D. **
Jessie Villanueva, Ph.D.
Ashani Weeraratna, Ph.D.

* Denotes program leader
** Denotes program co-leader
*** Denotes secondary appointment