Wistar Wire: Genes

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The molecular world that exists within our cells is constantly changing as cells adapt to the complex environment within our bodies. Wistar researchers work to unravel this confusing tangle of molecules, in order to understand how disease begins on a molecular level—and to develop new drugs for diseases such as cancer.
Cancer, Genes
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Congratulations are in order for The Cancer Genome Atlas Network, for their publication in Nature over the weekend that announced the most comprehensive analysis of breast cancer genetics yet published. Their findings have shown how the disease can be categorized by four distinct genetic profiles, and have identified genetic markers within each category that might advance cancer care by providing new, druggable targets.
Cancer, Genes
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A BRAF inhibitor known as vemurafenib (Zelboraf) has been touted as a breakthrough melanoma treatment. But for some patients, the price of success is a mutation that leads to the development of secondary skin cancers called squamous cell carcinomas. In an editorial in The New England Journal of Medicine, Wistar researcher Ashani Weeraratna, Ph.D., discusses the success of a new combination treatment.
Cancer, Genes, Melanoma
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A news segment featuring Wistar Professor Louise C. Showe, Ph.D., aired on CBS3 on December 21, 2011 in the five o'clock broadcast. The segment discussed her work toward developing a blood test for lung cancer.
Cancer, Genes