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The Wistar Institute

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Wistar Scientists Find Gut Microbe Byproduct Drives Antitumor Immunity

The team identified the metabolite TMAO drives immune activation in the tumor microenvironment and boosts response to immune checkpoint blockade therapy in pancreatic cancer. Rahul S. Shinde, D.V.M., Ph.D., Assistant Professor in the Immunology, Mic…
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The Wistar Institute Welcomes Michele A. Schiavoni, New Vice President of Communications & Marketing

PHILADELPHIA—(September 8, 2022)—The Wistar Institute is pleased to announce the appointment of Michele A. Schiavoni, M.S., as Vice President of Communications & Marketing, in a central leadership role that will bolster the visibility of the Ins…
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The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils Halts Cancer Progression and Metastasis

PHILADELPHIA — (Sept. 7, 2022) — Researchers in the laboratory of Yulia Nefedova, M.D., Ph.D., at The Wistar Institute and collaborators at Jubilant Therapeutics Inc. have uncovered a novel mechanism by which protein arginine deiminase 4 (PAD4) in n…
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Advancing Scientific Enterprise at Wistar’s Vaccine and Immunotherapy Center

With just over a year at The Wistar Institute under their respective scientific belts, innovator-scientists Amelia Escolano, Ph.D., and Daniel Claiborne, Ph.D., have been pushing the scientific envelope in Wistar laboratories using mouse models to p…
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A Wistar Journey Through the Past, Present, and Future of Immunization Work

Vaccines are a crucial public health tool in its’ arsenal against diseases. Resurgences of diseases long thought eradicated are popping up decades later in sewage waters here and abroad, and we’ve witnessed what the impact of war has on countries wh…
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Looking Inside the Gut for Answers to Long-COVID

This Q&A offers a behind the science peek into some of the long-term effects of COVID on the body influenced by the gut microbiome. In a paper published in JCI Insight, Mohamed Abdel-Mohsen, Ph.D., associate professor in The Wistar Institute Vac…
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Congratulations to the 2022 BTT Program and Fox BRT Apprenticeship Graduates!

On August 4, The Wistar Institute hosted a ceremony celebrating the 2022 graduates of the Biomedical Technician Training (BTT) Program and Fox Biomedical Research Technician (BRT) Apprenticeship. The hybrid event kicked off with a welcome by Dario A…
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Rahul Shinde, D.V.M, Ph.D., Receives Pancreatic Cancer Action Network Career Development Award

The Pancreatic Cancer Action Network announced that Rahul S. Shinde, D.V.M., Ph.D., Assistant Professor in the Immunology, Microenvironment & Metastasis Program of Wistar’s Ellen and Ronald Caplan Cancer Center, was bestowed the Pancreatic Cance…
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Wistar Receives Merit Extension from the National Cancer Institute

PHILADELPHIA — (August 2, 2022) — The National Cancer Institute (NCI) has granted a Merit Extension Award to The Wistar Institute’s Ellen and Ronald Caplan Cancer Center totaling more than $5 million. The Institute is the first NCI-designated Basic…
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Wistar Hosts Education Career Panel 

Several panelists from varied backgrounds spoke to Wistar trainees about their current positions as education professionals for science departments and institutions. What was the moment you knew you wanted to teach? How do you balance research and e…
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